Dataset Information
MWASTools: an R/bioconductor package for metabolome-wide association studies.
Ontology highlight
ABSTRACT: Summary
MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of metabolome-wide association studies results.Availability and implementation
The MWASTools R package is implemented in R (version??>?=3.4) and is available from Bioconductor: https://bioconductor.org/packages/MWASTools/.Contact
m.dumas@imperial.ac.uk.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Rodriguez-Martinez A
PROVIDER: S-EPMC6049002 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Publications
MWASTools: an R/bioconductor package for metabolome-wide association studies.
Bioinformatics (Oxford, England) 20180301 5
<h4>Summary</h4>MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of metabolome-wide ...[more]