Ontology highlight
ABSTRACT:
SUBMITTER: Miller BS
PROVIDER: S-EPMC6055620 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Miller Benjamin S BS Parolo Claudio C Turbé Valérian V Keane Candice E CE Gray Eleanor R ER McKendry Rachel A RA
Chemistry (Weinheim an der Bergstrasse, Germany) 20180608 39
A novel ultra-low-cost biochemical analysis platform to quantify protein dissociation binding constants and kinetics using paper microfluidics is reported. This approach marries video imaging with one of humankind's oldest materials: paper, requiring no large, expensive laboratory equipment, complex microfluidics or external power. Temporal measurements of nanoparticle-antibody conjugates binding on paper is found to follow the Langmuir Adsorption Model. This is exploited to measure a series of ...[more]