Ontology highlight
ABSTRACT:
SUBMITTER: Guo Z
PROVIDER: S-EPMC6058515 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Guo Zhaoming Z Li Wenqing W Yuan Yue Y Zheng Kun K Tang Yu Y Ma Kun K Cui Changhao C Wang Li L He Bing B Zhang Qiang Q
Drug delivery 20181101 1
How to overcome drug resistance and prevent tumor metastasis is key to the success of malignant tumor therapy. In this paper, ADH-1 peptide-modified liposomes (A-LP) have been successfully constructed for restoring chemosensitivity and suppressing cancer cell migration. With a particle size of about 90 nm, this functionalized nanocarrier was loaded with fluorescent probe or paclitaxel (PTX). Cellular uptake studies showed that A-LP facilitated the delivery of anticancer drug to tumor cells under ...[more]