Bona fide receptor for hepatitis B and D viral infections: Mechanism, research models and molecular drug targets.
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ABSTRACT:
SUBMITTER: Yu Y
PROVIDER: S-EPMC6062556 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Publications
Bona fide receptor for hepatitis B and D viral infections: Mechanism, research models and molecular drug targets.
Yu Yueran Y Li Shangda S Liang Weifeng W
Emerging microbes & infections 20180726 1
Hepatitis B infections have become a serious public health issue globally, and the current first-line antiviral treatment for this disease is not a true cure. Recently, sodium taurocholate cotransporting polypeptide (NTCP), a liver-specific bile acid transporter, was identified as a bona fide receptor for hepatitis B virus (HBV) and its satellite virus, hepatitis delta virus (HDV). Identification of the HBV receptor has led to the development of robust cell cultures and provides a potential targ ...[more]
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