Unknown

Dataset Information

0

Recent advances in the understanding and treatment of acute myeloid leukemia.


ABSTRACT: Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease that has a poor prognosis. Recent advances in genomics and molecular biology have led to a greatly improved understanding of the disease. Until 2017, there had been no new drugs approved for AML in decades. Here, we review novel drug targets in AML with a focus on epigenetic-targeted therapies in pre-clinical and clinical development as well as the recent new drug approvals.

SUBMITTER: Watts J 

PROVIDER: S-EPMC6081972 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC4923501 | biostudies-literature
| S-EPMC6219429 | biostudies-literature
| S-EPMC5026289 | biostudies-literature
| S-EPMC9032060 | biostudies-literature
| S-EPMC8973851 | biostudies-literature
| S-EPMC5931274 | biostudies-literature
| S-EPMC6039949 | biostudies-other
| S-EPMC6467350 | biostudies-literature
| S-EPMC6833142 | biostudies-literature
| S-EPMC5933364 | biostudies-other