Ontology highlight
ABSTRACT:
SUBMITTER: Ogawa M
PROVIDER: S-EPMC6099671 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Ogawa Mitsutaka M Senoo Yuya Y Ikeda Kazutaka K Takeuchi Hideyuki H Okajima Tetsuya T
Molecules (Basel, Switzerland) 20180717 7
Extracellular <i>O</i>-GlcNAc is a novel class of modification catalyzed by epidermal growth factor-like (EGF)-domain specific <i>O</i>-GlcNAc transferase (EOGT). In mammals, EOGT is required for ligand-mediated Notch signaling for vascular development. Previous studies have revealed that <i>O</i>-GlcNAc in mammalian cultured cells is subject to subsequent glycosylation, which may impose additional layers of regulation. This study aimed to analyze the <i>O</i>-GlcNAc glycans of <i>Drosophila</i> ...[more]