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Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata.

ABSTRACT: A novel isoquinoline alkaloid, mahimbrine A, possessing a rare benzotropolone framing scaffold, was isolated from the endemic plant of Mahonia imbricata. Its structure was established on the basis of extensive spectroscopic analysis. A plausible biosynthetic route of mahimbrine A was proposed. Mahimbrine A showed no antimicrobial activity at the concentration of 1 mg/mL.

SUBMITTER: Zhang MS

PROVIDER: S-EPMC6100064 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from <i>Mahonia imbricata</i>.

Zhang Mao-Sheng MS Deng Yan Y Fu Shao-Bin SB Guo Da-Le DL Xiao Shi-Ji SJ

Molecules (Basel, Switzerland) 20180626 7

A novel isoquinoline alkaloid, mahimbrine A, possessing a rare benzotropolone framing scaffold, was isolated from the endemic plant of <i>Mahonia imbricata</i>. Its structure was established on the basis of extensive spectroscopic analysis. A plausible biosynthetic route of mahimbrine A was proposed. Mahimbrine A showed no antimicrobial activity at the concentration of 1 mg/mL. ...[more]

PMID: 29949909

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