Unknown

Dataset Information

0

Aspergoterpenins A?D: Four New Antimicrobial Bisabolane Sesquiterpenoid Derivatives from an Endophytic Fungus Aspergillus versicolor.

ABSTRACT: Aspergoterpenins A?D (1?4), four new bisabolane sesquiterpenoid derivatives, were obtained from the endophytic fungus, Aspergillus versicolor, together with eight known compounds (5?12), and their structures were elucidated by a comprehensive analysis of their NMR (Nuclear Magnetic Resonance), MS (Mass Spectrum) and CD (Circular Dichroism) spectra. Aspergoterpenin A (1) was the first example with a characteristic ketal bridged-ring part in the degraded natural bisabolane-type sesquiterpene structures. The compounds 1?12 displayed no significant activities against four cancer cell lines (A549, Caski, HepG2 and MCF-7). Further, the antimicrobial activities to Erwinia carotovora sub sp. Carotovora were evaluated, and the results showed that compounds 1?12 displayed antimicrobial activities with MIC values ranging from 15.2 to 85.2 ?g/mL.

SUBMITTER: Guo ZY 

PROVIDER: S-EPMC6100428 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Aspergoterpenins A⁻D: Four New Antimicrobial Bisabolane Sesquiterpenoid Derivatives from an Endophytic Fungus <i>Aspergillus versicolor</i>.

Guo Zhi-Yong ZY   Tan Ming-Hui MH   Liu Cheng-Xiong CX   Lv Meng-Meng MM   Deng Zhang-Shuang ZS   Cao Fei F   Zou Kun K   Proksch Peter P  

Molecules (Basel, Switzerland) 20180528 6

Aspergoterpenins A⁻D (<b>1</b>⁻<b>4</b>), four new bisabolane sesquiterpenoid derivatives, were obtained from the endophytic fungus, <i>Aspergillus versicolor</i>, together with eight known compounds (<b>5</b>⁻<b>1</b><b>2</b>), and their structures were elucidated by a comprehensive analysis of their NMR (Nuclear Magnetic Resonance), MS (Mass Spectrum) and CD (Circular Dichroism) spectra. Aspergoterpenin A (<b>1</b>) was the first example with a characteristic ketal bridged-ring part in the deg  ...[more]

Similar Datasets

Unknown Antimicrobial Sesquiterpenoid Derivatives and Monoterpenoids from the Deep-Sea Sediment-Derived Fungus Aspergillus versicolor SD-330.
| S-EPMC6836274 | biostudies-literature
Unknown Epigenetic Agents Trigger the Production of Bioactive Nucleoside Derivatives and Bisabolane Sesquiterpenes From the Marine-Derived Fungus <i>Aspergillus versicolor</i>.
| S-EPMC7002437 | biostudies-literature
Unknown Aniquinazolines A-D, four new quinazolinone alkaloids from marine-derived endophytic fungus Aspergillus nidulans.
| S-EPMC3736446 | biostudies-literature
Unknown α-Glucosidase Inhibitors: Diphenyl Ethers and Phenolic Bisabolane Sesquiterpenoids from the Mangrove Endophytic Fungus Aspergillus flavus QQSG-3.
| S-EPMC6165285 | biostudies-literature
Unknown Phomopsichin A-D; Four New Chromone Derivatives from Mangrove Endophytic Fungus Phomopsis sp. 33.
| S-EPMC5128758 | biostudies-literature
Unknown New Diketopiperazines from a Marine-Derived Fungus Strain Aspergillus versicolor MF180151.
| S-EPMC6562876 | biostudies-literature
Unknown Two New Quinazoline Derivatives from the Moss Endophytic Fungus Aspergillus sp. and Their Anti-inflammatory Activity.
| S-EPMC7933300 | biostudies-literature
Unknown Kipukasins, nucleoside derivatives from Aspergillus versicolor.
| S-EPMC2532754 | biostudies-literature
Unknown Antimicrobial and Antioxidant Polyketides from a Deep-Sea-Derived Fungus <i>Aspergillus versicolor</i> SH0105.
| S-EPMC7764742 | biostudies-literature
Unknown Antibacterial bisabolane-type sesquiterpenoids from the sponge-derived fungus Aspergillus sp.
| S-EPMC3280534 | biostudies-literature