Ontology highlight
ABSTRACT:
SUBMITTER: Shen XH
PROVIDER: S-EPMC6105682 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Shen Xing-Hui XH Jin Yong-Xun YX Liang Shuang S Kwon Jeong-Woo JW Zhu Ji-Wei JW Lei Lei L Lei Lei L Kim Nam-Hyung NH
Scientific reports 20180822 1
Autophagy is an essential cellular mechanism that degrades cytoplasmic proteins and organelles to recycle their components; however, the contribution of autophagy during meiosis has not been studied in porcine oocytes maturing in vitro. In this study, we observed that the autophagy-related gene, LC3, was expressed in porcine oocytes during maturation for 44 h in vitro. Knockdown of the autophagy-related gene, BECN1, reduced both BECN1 and LC3 protein expression levels. Moreover, BECN1 knockdown ...[more]