Ontology highlight
ABSTRACT:
SUBMITTER: Kordestani F
PROVIDER: S-EPMC6106732 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Kordestani Fahimeh F Mazloomi Sahar S Mortazavi Yousef Y Mazloomzadeh Saeideh S Fathi Mojtaba M Rahmanpour Haleh H Nazarian Abolfazl A
BMC medical genetics 20180822 1
<h4>Background</h4>Polycystic ovary syndrome (PCOS) is the main cause of female infertility. Interactions among genetic, biochemical, and immunological factors can affect the pathogenesis of PCOS. As a proinflammatory cytokine, tumor necrosis factor-α (TNF-α) plays an important role in this regard. The present study aimed to evaluate the association of the rs361525 gene single-nucleotide polymorphism (SNP) and TNF-α serum levels with the hormonal and biochemical characteristics of PCOS in Irania ...[more]