Ontology highlight
ABSTRACT:
SUBMITTER: Watanabe M
PROVIDER: S-EPMC6121510 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20180810 8
Retinoid X receptor (RXR) antagonists are not only useful as chemical tools for biological research, but are also candidate drugs for the treatment of various diseases, including diabetes and allergies, although no RXR antagonist has yet been approved for clinical use. In this review, we present a brief overview of RXR structure, function, and target genes, and describe currently available RXR antagonists, their structural classification, and their evaluation, focusing on the latest research. ...[more]