Ontology highlight
ABSTRACT:
SUBMITTER: Ahmed M
PROVIDER: S-EPMC6132783 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Ahmed Madiha M Ul Haq Ihsan I Faisal Muhammad M Waseem Durdana D Taqi Malik Mumtaz MM
Journal of molecular neuroscience : MN 20180722 4
Single nucleotide polymorphism in OPRM1 gene is associated with hedonic and reinforcing consequences of opioids. Risk and protective alleles may vary in different populations. One hundred healthy controls and 100 opioids (predominantly heroin) addicts from Pakistani origin were genotyped for A118G (N40D) polymorphism in OPRM1. Structural and functional impact of the polymorphism on encoded protein was predicted by in silico analysis. Results show significant association between homozygous GG gen ...[more]