Ontology highlight
ABSTRACT:
SUBMITTER: Mariani A
PROVIDER: S-EPMC6152610 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20180703 28
Investigations into the chemical origin of life have recently benefitted from a holistic approach in which possible atmospheric, organic, and inorganic systems chemistries are taken into consideration. In this way, we now report that a selective phosphate activating agent, namely methyl isocyanide, could plausibly have been produced from simple prebiotic feedstocks. We show that methyl isocyanide drives the conversion of nucleoside monophosphates to phosphorimidazolides under potentially prebiot ...[more]