Ontology highlight
ABSTRACT:
SUBMITTER: Tanaka T
PROVIDER: S-EPMC6156492 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Aging cell 20180711 5
To characterize the proteomic signature of chronological age, 1,301 proteins were measured in plasma using the SOMAscan assay (SomaLogic, Boulder, CO, USA) in a population of 240 healthy men and women, 22-93 years old, who were disease- and treatment-free and had no physical and cognitive impairment. Using a p ≤ 3.83 × 10<sup>-5</sup> significance threshold, 197 proteins were positively associated, and 20 proteins were negatively associated with age. Growth differentiation factor 15 (GDF15) had ...[more]