Ontology highlight
ABSTRACT:
SUBMITTER: Drawitsch F
PROVIDER: S-EPMC6158011 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Drawitsch Florian F Karimi Ali A Boergens Kevin M KM Helmstaedter Moritz M
eLife 20180814
The labeling and identification of long-range axonal inputs from multiple sources within densely reconstructed electron microscopy (EM) datasets from mammalian brains has been notoriously difficult because of the limited color label space of EM. Here, we report FluoEM for the identification of multi-color fluorescently labeled axons in dense EM data without the need for artificial fiducial marks or chemical label conversion. The approach is based on correlated tissue imaging and computational ma ...[more]