Ontology highlight
ABSTRACT:
SUBMITTER: Lin F
PROVIDER: S-EPMC6166529 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Lin Fan F de Gooijer Mark C MC Hanekamp Diana D Brandsma Dieta D Beijnen Jos H JH van Tellingen Olaf O
CNS oncology 20130501 3
High-grade gliomas are the most common type of primary brain tumor and are among the most lethal types of human cancer. Most patients with a high-grade glioma have glioblastoma multiforme (GBM), the most malignant glioma subtype that is associated with a very aggressive disease course and short overall survival. Standard treatment of newly diagnosed GBM involves surgery followed by chemoradiation with temozolomide. However, despite this extensive treatment the mean overall survival is still only ...[more]