Ontology highlight
ABSTRACT:
SUBMITTER: Koenigsberg AL
PROVIDER: S-EPMC6187633 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Koenigsberg Andrea L AL Heldwein Ekaterina E EE
The Journal of biological chemistry 20180830 41
In all herpesviruses, the space between the capsid shell and the lipid envelope is occupied by the unique tegument layer composed of proteins that, in addition to structural roles, play many other roles in the viral replication. UL37 is a highly conserved tegument protein that has activities ranging from virion morphogenesis to directional capsid trafficking to manipulation of the host innate immune response and binds multiple partners. The N-terminal half of UL37 (UL37N) has a compact bean-shap ...[more]