Ontology highlight
ABSTRACT:
SUBMITTER: Pervolaraki E
PROVIDER: S-EPMC6194117 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Pervolaraki Eleftheria E Dachtler James J Anderson Richard A RA Holden Arun V AV
Scientific reports 20181018 1
The human heart develops through complex mechanisms producing morphological and functional changes during gestation. We have recently demonstrated using diffusion tensor MRI that over the relatively short space of 40 days, between 100-140 days gestational age, the ventricular myocardium transforms from a disorganised tissue to the ordered structure characteristic of mature cardiac tissue. However, the genetic basis underpinning this maturation is unclear. Herein, we have used RNA-Seq to establis ...[more]