Ontology highlight
ABSTRACT:
SUBMITTER: Ye X
PROVIDER: S-EPMC6199349 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Ye Xin X Zhou Xu-Jie XJ Zhang Hong H
Frontiers in immunology 20181017
Autophagy is a highly conserved process that degrades certain intracellular contents in both physiological and pathological conditions. Autophagy-related proteins (<i>ATG</i>) are key players in this pathway, among which <i>ATG5</i> is indispensable in both canonical and non-canonical autophagy. Recent studies demonstrate that <i>ATG5</i> modulates the immune system and crosstalks with apoptosis. However, our knowledge of the pathogenesis and regulatory mechanisms of autophagy in various immune ...[more]