Ontology highlight
ABSTRACT:
SUBMITTER: Du X
PROVIDER: S-EPMC6204774 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Du Xiaochen X Huang Jianjun J Nechaev Anton A AA Yao Ruwei R Gong Jing J Van der Eycken Erik V EV Pereshivko Olga P OP Peshkov Vsevolod A VA
Beilstein journal of organic chemistry 20181004
A series of propargylamides containing an electron-rich benzene ring was prepared through the Ugi reaction of 3,5-dimethoxyaniline with various propiolic acids, aldehydes and isocyanides. Subjecting these adducts to a gold-catalyzed intramolecular alkyne hydroarylation process allowed to efficiently construct the 2-quinolone core bearing a branched substituent on the nitrogen atom. ...[more]