Ontology highlight
ABSTRACT:
SUBMITTER: Zhen X
PROVIDER: S-EPMC6213349 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Marine drugs 20181001 10
By treating with histone-deacetylase inhibitor valproate sodium, three new heterdimeric tetrahydroxanthone⁻chromanone lactones chrysoxanthones A⁻C (<b>1</b>⁻<b>3</b>), along with 17 known compounds were isolated from a sponge-associated <i>Penicillium chrysogenum</i> HLS111. The planar structures of chrysoxanthones A⁻C were elucidated by means of spectroscopic analyses, including MS, 1D, and 2D NMR. Their absolute configurations were established by electronic circular dichroism (ECD) calculation ...[more]