Ontology highlight
ABSTRACT:
SUBMITTER: Shellard A
PROVIDER: S-EPMC6218007 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20181001 6412
Collective cell chemotaxis, the directed migration of cell groups along gradients of soluble chemical cues, underlies various developmental and pathological processes. We use neural crest cells, a migratory embryonic stem cell population whose behavior has been likened to malignant invasion, to study collective chemotaxis in vivo. Studying <i>Xenopus</i> and zebrafish, we have shown that the neural crest exhibits a tensile actomyosin ring at the edge of the migratory cell group that contracts in ...[more]