Ontology highlight
ABSTRACT:
SUBMITTER: Stout K
PROVIDER: S-EPMC6222891 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Stout Kristen K Bernaskova Marketa M Miller Gary W GW Hufner Antje A Schuehly Wolfgang W
Molecules (Basel, Switzerland) 20181004 10
In traditional Asian medicinal systems, preparations of the root and stem bark of <i>Magnolia</i> species are widely used to treat anxiety and other nervous disturbances. The biphenyl-type neolignans honokiol and magnolol are the main constituents of <i>Magnolia</i> bark extracts. In the central nervous system, <i>Magnolia</i> bark preparations that contain honokiol are thought to primarily interact with γ-aminobutyric acid A (GABA<sub>A</sub>) receptors. However, stress responses inherently inv ...[more]