Can mesenchymal stem cell lysate reverse aging?
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ABSTRACT:
SUBMITTER: Hsu MF
PROVIDER: S-EPMC6224235 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Can mesenchymal stem cell lysate reverse aging?
Hsu Ming-Fen MF Yu Szu-Hsien SH Chuang Sheng-Ju SJ Kuo Tom Kwang-Chun TK Singal Pawan K PK Huang Chih-Yang CY Kao Chung-Lan CL Kuo Chia-Hua CH
Aging 20181001 10
Recent findings regarding uses of adipose-derived mesenchymal stem cell (MSC)-lysate on weight loss and improved glucose tolerance in mice on a high-fat diet suggest an encouraging possibility of using MSC lysate for an anti-aging intervention in humans. However, weight loss and lipopenia during late life can be as life-threatening as hyperglycemia during early adulthood. For this 3-year lifelong experiment, a total of 92 rats were randomized into the vehicle-injected group (F=22; M=24) and the ...[more]
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