Ontology highlight
ABSTRACT:
SUBMITTER: Wang Q
PROVIDER: S-EPMC6224603 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Wang Qianmin Q Taschner Michael M Ganzinger Kristina A KA Kelley Charlotte C Villasenor Alethia A Heymann Michael M Schwille Petra P Lorentzen Esben E Mizuno Naoko N
Nature communications 20181108 1
The cilium is an organelle used for motility and cellular signaling. Intraflagellar transport (IFT) is a process to move ciliary building blocks and signaling components into the cilium. How IFT controls the movement of ciliary components is currently poorly understood. IFT172 is the largest IFT subunit essential for ciliogenesis. Due to its large size, the characterization of IFT172 has been challenging. Using giant unilamellar vesicles (GUVs), we show that IFT172 is a membrane-interacting prot ...[more]