Ontology highlight
ABSTRACT:
SUBMITTER: Bouvier G
PROVIDER: S-EPMC6231762 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Bouvier Guy G Aljadeff Johnatan J Clopath Claudia C Bimbard Célian C Ranft Jonas J Blot Antonin A Nadal Jean-Pierre JP Brunel Nicolas N Hakim Vincent V Barbour Boris B
eLife 20181112
The cerebellum aids the learning of fast, coordinated movements. According to current consensus, erroneously active parallel fibre synapses are depressed by complex spikes signalling movement errors. However, this theory cannot solve the <i>credit assignment problem</i> of processing a global movement evaluation into multiple cell-specific error signals. We identify a possible implementation of an algorithm solving this problem, whereby spontaneous complex spikes perturb ongoing movements, creat ...[more]