Ontology highlight
ABSTRACT:
SUBMITTER: Dix SR
PROVIDER: S-EPMC6232143 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Dix Samuel R SR Owen Hayley J HJ Sun Ruyue R Ahmad Asma A Shastri Sravanthi S Spiewak Helena L HL Mosby Daniel J DJ Harris Matthew J MJ Batters Sarah L SL Brooker Thomas A TA Tzokov Svetomir B SB Sedelnikova Svetlana E SE Baker Patrick J PJ Bullough Per A PA Rice David W DW Thomas Mark S MS
Nature communications 20181112 1
The type VI secretion system (T6SS) is a multi-protein complex that injects bacterial effector proteins into target cells. It is composed of a cell membrane complex anchored to a contractile bacteriophage tail-like apparatus consisting of a sharpened tube that is ejected by the contraction of a sheath against a baseplate. We present structural and biochemical studies on TssA subunits from two different T6SSs that reveal radically different quaternary structures in comparison to the dodecameric E ...[more]