Ontology highlight
ABSTRACT:
SUBMITTER: Warfield KL
PROVIDER: S-EPMC6249597 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Warfield Kelly L KL Howell Katie A KA Vu Hong H Geisbert Joan J Wong Gary G Shulenin Sergey S Sproule Stephanie S Holtsberg Frederick W FW Leung Daisy W DW Amarasinghe Gaya K GK Swenson Dana L DL Bavari Sina S Kobinger Gary P GP Geisbert Thomas W TW Aman M Javad MJ
The Journal of infectious diseases 20181101 suppl_5
<h4>Background</h4>Several vaccine platforms have been successfully evaluated for prevention of Ebola virus (EBOV) disease (EVD) in nonhuman primates and humans. Despite remarkable efficacy by multiple vaccines, the immunological correlates of protection against EVD are incompletely understood.<h4>Methods</h4>We systematically evaluated the antibody response to various EBOV proteins in 79 nonhuman primates vaccinated with various EBOV vaccine platforms. We evaluated the serum immunoglobulin (Ig) ...[more]