Ontology highlight
ABSTRACT:
SUBMITTER: Verzele D
PROVIDER: S-EPMC6264362 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20111207 12
We present three versatile solid-supported scaffold building blocks based on the (deoxy)cholic acid framework and decorated with handles for further derivatization by modern ligation techniques such as click chemistry, Staudinger ligation or native chemical ligation. Straightforward procedures are presented for the synthesis and analysis of the steroid constructs. These building blocks offer a new, facile and shorter access route to bile acid-peptide conjugates on solid-phase with emphasis on he ...[more]