Ontology highlight
ABSTRACT:
SUBMITTER: Abdo M
PROVIDER: S-EPMC6270073 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Abdo Mohannad M Sun Zhexun Z Knapp Spencer S
Molecules (Basel, Switzerland) 20130204 2
We describe the synthesis of the N-(2-seleninatoethyl) amide of N-Boc-phenylalanine, serving here as a peptide model, and its reductive coupling reactions under mild conditions with unprotected thiouridine and glutathione. Selenosulfide products such as these comprise reversibly conjugated bio-components, and can potentially find uses as probes of biological function, such as enzyme inhibitors, delivery systems, or structural mimics. ...[more]