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The plasma peptidome.


ABSTRACT:

SUBMITTER: Dufresne J 

PROVIDER: S-EPMC6271647 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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<h4>Background</h4>It may be possible to discover new diagnostic or therapeutic peptides or proteins from blood plasma using LC-ESI-MS/MS to identify, with a linear quadrupole ion trap to identify, quantify and compare the statistical distributions of peptides cleaved ex vivo from plasma samples from different clinical populations.<h4>Methods</h4>A systematic method for the organic fractionation of plasma peptides was applied to identify and quantify the endogenous tryptic peptides from human pl  ...[more]

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