Ontology highlight
ABSTRACT:
SUBMITTER: Liu T
PROVIDER: S-EPMC6273136 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20160517 5
An efficient and convenient method to synthesize highly functionalized 3,7'-bisindole derivatives has been developed via a Michael addition and cyclic condensation reaction of heterocyclic ketene aminals (HKAs) with 2-(1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dione derivatives in ethanol-based solvents at room temperature. This strategy provides an efficient, environmentally friendly approach for easy access to various novel 3,7'-bisindole derivatives in moderate to good yields. ...[more]