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Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans.

ABSTRACT: A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.

SUBMITTER: Lin MH

PROVIDER: S-EPMC6274509 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

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Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans.

Lin Mei-Huey MH Chen Yu-Chun YC Chiu Shih-Hao SH Chen Yun-Fan YF Chuang Tsung-Hsun TH

Molecules (Basel, Switzerland) 20161221 12

A new strategy for cyclopenta[<i>b</i>]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[<i>b</i>]furan targets. ...[more]

PMID: 28009840

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