Ontology highlight
ABSTRACT:
SUBMITTER: Yang C
PROVIDER: S-EPMC6274816 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20181118 11
The quaternary transition between the relaxed (R) and tense (T) states of heme-binding proteins is a textbook example for the allosteric structural transition. Homodimeric hemoglobin (HbI) from <i>Scapharca inaequivalvis</i> is a useful model system for investigating the allosteric behavior because of the relatively simple quaternary structure. To understand the cooperative transition of HbI, wild-type and mutants of HbI have been studied by using time-resolved X-ray solution scattering (TRXSS), ...[more]