Ontology highlight
ABSTRACT:
SUBMITTER: Kim M
PROVIDER: S-EPMC6278647 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Kim Minjun M Jang Jaebong J Choi Goyoung G Chung Sungkyun S Lim Changjin C Hur Joonseong J Kim Hyun Su HS Na Younghwa Y Son Woo Sung WS Suh Young-Ger YG Jung Jong-Wha JW Kim Seok-Ho SH
Molecules (Basel, Switzerland) 20181119 11
α-Vinyl or α-acetylenyl azacycles were easily synthesized from 7- to 9-membered lactams and 6- to 9-membered lactams via <i>N</i>,<i>O</i>-acetal trimethylsilyl (TMS) ethers. Organocopper and organostannane reagents afforded reasonable yields for the respective <i>N</i>-acyliminium ion vinylation and acetylenylation intermediates generated from <i>N</i>,<i>O</i>-acetal TMS ethers in the presence of a Lewis acid. ...[more]