Ontology highlight
ABSTRACT:
SUBMITTER: Biamonte F
PROVIDER: S-EPMC6281584 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Biamonte Flavia F Battaglia Anna Martina AM Zolea Fabiana F Oliveira Duarte Mendes DM Aversa Ilenia I Santamaria Gianluca G Giovannone Emilia Dora ED Rocco Gaetano G Viglietto Giuseppe G Costanzo Francesco F
Cell death & disease 20181205 12
Ferritin is a nanocage protein composed by the variable assembly of 24 heavy and light subunits. As major intracellular iron storage protein, ferritin has been studied for many years in the context of iron metabolism. However, recent evidences have highlighted its role, in particular that of the heavy subunit (FHC), in pathways related to cancer development and progression, such as cell proliferation, growth suppressor evasion, cell death inhibition, and angiogenesis. At least partly, the involv ...[more]