Ontology highlight
ABSTRACT:
SUBMITTER: Jones MS
PROVIDER: S-EPMC3909977 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Jones Morris S MS Carter J Mark JM
Advances in bioinformatics 20140102
Listeria monocytogenes is a gram-positive, foodborne bacterium responsible for disease in humans and animals. Listeriolysin O (LLO) is a required virulence factor for the pathogenic effects of L. monocytogenes. Bioinformatics revealed conserved putative epitopes of LLO that could be used to develop monoclonal antibodies against LLO. Continuous and discontinuous epitopes were located by using four different B-cell prediction algorithms. Three-dimensional molecular models were generated to more pr ...[more]