Ontology highlight
ABSTRACT:
SUBMITTER: Kerr D
PROVIDER: S-EPMC6290684 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Biochimica et biophysica acta. Biomembranes 20180618 10
There is a diverse class of peripheral membrane-binding proteins that specifically bind phosphatidylserine (PS), a lipid that signals apoptosis or cell fusion depending on the membrane context of its presentation. PS-receptors are specialized for particular PS-presenting pathways, indicating that they might be sensitive to the membrane context. In this review, we describe a combination of thermodynamic, structural, and computational techniques that can be used to investigate the mechanisms under ...[more]