Ontology highlight
ABSTRACT:
SUBMITTER: Sumi A
PROVIDER: S-EPMC6291457 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Sumi Angughali A Hayes Peran P D'Angelo Arturo A Colombelli Julien J Salbreux Guillaume G Dierkes Kai K Solon Jérôme J
Developmental cell 20181101 4
During epithelial contraction, cells generate forces to constrict their surface and, concurrently, fine-tune the length of their adherens junctions to ensure force transmission. While many studies have focused on understanding force generation, little is known on how junctional length is controlled. Here, we show that, during amnioserosa contraction in Drosophila dorsal closure, adherens junctions reduce their length in coordination with the shrinkage of apical cell area, maintaining a nearly co ...[more]