Ontology highlight
ABSTRACT:
SUBMITTER: Walker-Samuel S
PROVIDER: S-EPMC6298581 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Walker-Samuel Simon S Roberts Thomas A TA Ramasawmy Rajiv R Burrell Jake S JS Johnson Sean Peter SP Siow Bernard M BM Richardson Simon S Gonçalves Miguel R MR Pendse Douglas D Robinson Simon P SP Pedley R Barbara RB Lythgoe Mark F MF
Cancer research 20180109 7
Several distinct fluid flow phenomena occur in solid tumors, including intravascular blood flow and interstitial convection. Interstitial fluid pressure is often raised in solid tumors, which can limit drug delivery. To probe low-velocity flow in tumors resulting from raised interstitial fluid pressure, we developed a novel MRI technique named convection-MRI, which uses a phase-contrast acquisition with a dual-inversion vascular nulling preparation to separate intra- and extravascular flow. Here ...[more]