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Operation and Performance of a Mass-Selective Cryogenic Linear Ion Trap.

ABSTRACT: We report on the performance of a cryogenic 2D linear ion trap (cryoLIT) that is shown to be mass-selective in the temperature range of 17-295 K. As the cryoLIT is cooled, the ejection voltages during the mass instability scan decrease, which results in an effective mass shift to lower m/z relative to room temperature. This is attributed to a decrease in trap radius caused by thermal contraction. Additionally, the cryoLIT generates reproducible mass spectra from day-to-day, and is capable of performing stored waveform inverse Fourier transform (SWIFT) mass isolation of fragile N2-tagged ions for the purpose of background-free infrared dissociation spectroscopy. Graphical Abstract ?.

SUBMITTER: Tesler LF 

PROVIDER: S-EPMC6301008 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Operation and Performance of a Mass-Selective Cryogenic Linear Ion Trap.

Tesler Larry F LF   Cismesia Adam P AP   Bell Matthew R MR   Bailey Laura S LS   Polfer Nicolas C NC  

Journal of the American Society for Mass Spectrometry 20180730 11

We report on the performance of a cryogenic 2D linear ion trap (cryoLIT) that is shown to be mass-selective in the temperature range of 17-295 K. As the cryoLIT is cooled, the ejection voltages during the mass instability scan decrease, which results in an effective mass shift to lower m/z relative to room temperature. This is attributed to a decrease in trap radius caused by thermal contraction. Additionally, the cryoLIT generates reproducible mass spectra from day-to-day, and is capable of per  ...[more]

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