Ontology highlight
ABSTRACT:
SUBMITTER: Westfall J
PROVIDER: S-EPMC6320669 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Westfall Jennifer J Yates Jennifer L JL Van Slyke Greta G Ehrbar Dylan D Measey Thomas T Straube Richard R Donini Oreola O Mantis Nicholas J NJ
Vaccine 20180829 40
Biodefense vaccine are destined to be stockpiled for periods of time and deployed in the event of a public health emergency. In this report, we compared the potency of liquid and lyophilized (thermostabilized) formulations of a candidate ricin toxin subunit vaccine, RiVax, adsorbed to aluminum salts adjuvant, over a 12-month period. The liquid and lyophilized formulations were stored at stressed (40 °C) and unstressed (4 °C) conditions and evaluated at 3, 6 and 12-month time points for potency i ...[more]