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Flabelliferins A and B, sesterterpenoids from the South Pacific sponge Carteriospongia flabellifera.

ABSTRACT: Two new sesterterpenoids named flabelliferins A (1) and B (2) were isolated from the lipophilic extract of the sponge Cateriospongia flabellifera, collected in the South Pacific near Vanuatu. The structure and absolute configuration of these two compounds were assigned by a combination of one- and two-dimensional NMR spectroscopy and by Mosher's ester analysis. Flabelliferin A (1) has a rare 25-homocheilanthane carbon skeleton, while flabelliferin B (2) is a 24-nor-25-homoscalarane sesterterpenoid.

SUBMITTER: Diyabalanage T

PROVIDER: S-EPMC6322203 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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Flabelliferins A and B, sesterterpenoids from the South Pacific sponge Carteriospongia flabellifera.

Diyabalanage Thushara T Ratnayake Ranjala R Bokesch Heidi R HR Ransom Tanya T TT Henrich Curtis J CJ Beutler John A JA McMahon James B JB Gustafson Kirk R KR

Journal of natural products 20120726 8

Two new sesterterpenoids named flabelliferins A (1) and B (2) were isolated from the lipophilic extract of the sponge Cateriospongia flabellifera, collected in the South Pacific near Vanuatu. The structure and absolute configuration of these two compounds were assigned by a combination of one- and two-dimensional NMR spectroscopy and by Mosher's ester analysis. Flabelliferin A (1) has a rare 25-homocheilanthane carbon skeleton, while flabelliferin B (2) is a 24-nor-25-homoscalarane sesterterpeno ...[more]

PMID: 22834941

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