Dataset Information

POSTAR2: deciphering the post-transcriptional regulatory logics.

ABSTRACT: Post-transcriptional regulation of RNAs is critical to the diverse range of cellular processes. The volume of functional genomic data focusing on post-transcriptional regulation logics continues to grow in recent years. In the current database version, POSTAR2 (http://lulab.life.tsinghua.edu.cn/postar), we included the following new features and data: updated ∼500 CLIP-seq datasets (∼1200 CLIP-seq datasets in total) from six species, including human, mouse, fly, worm, Arabidopsis and yeast; added a new module 'Translatome', which is derived from Ribo-seq datasets and contains ∼36 million open reading frames (ORFs) in the genomes from the six species; updated and unified post-transcriptional regulation and variation data. Finally, we improved web interfaces for searching and visualizing protein-RNA interactions with multi-layer information. Meanwhile, we also merged our CLIPdb database into POSTAR2. POSTAR2 will help researchers investigate the post-transcriptional regulatory logics coordinated by RNA-binding proteins and translational landscape of cellular RNAs.

SUBMITTER: Zhu Y

PROVIDER: S-EPMC6323971 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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POSTAR2: deciphering the post-transcriptional regulatory logics.

Zhu Yumin Y Xu Gang G Yang Yucheng T YT Xu Zhiyu Z Chen Xinduo X Shi Binbin B Xie Daoxin D Lu Zhi John ZJ Wang Pengyuan P

Nucleic acids research 20190101 D1

Post-transcriptional regulation of RNAs is critical to the diverse range of cellular processes. The volume of functional genomic data focusing on post-transcriptional regulation logics continues to grow in recent years. In the current database version, POSTAR2 (http://lulab.life.tsinghua.edu.cn/postar), we included the following new features and data: updated ∼500 CLIP-seq datasets (∼1200 CLIP-seq datasets in total) from six species, including human, mouse, fly, worm, Arabidopsis and yeast; adde ...[more]

PMID: 30239819

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Dataset Information

POSTAR2: deciphering the post-transcriptional regulatory logics.

Publications

POSTAR2: deciphering the post-transcriptional regulatory logics.

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