Ontology highlight
ABSTRACT:
SUBMITTER: Keiflin R
PROVIDER: S-EPMC6324975 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Keiflin Ronald R Pribut Heather J HJ Shah Nisha B NB Janak Patricia H PH
Current biology : CB 20181220 1
Dopamine (DA) neurons in the ventral tegmental area (VTA) and substantia nigra (SNc) encode reward prediction errors (RPEs) and are proposed to mediate error-driven learning. However, the learning strategy engaged by DA-RPEs remains controversial. RPEs might imbue predictive cues with pure value, independently of representations of their associated outcome. Alternatively, RPEs might promote learning about the sensory features (the identity) of the rewarding outcome. Here, we show that, although ...[more]