Ontology highlight
ABSTRACT:
SUBMITTER: Baquero E
PROVIDER: S-EPMC6327110 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Baquero Eduard E Fedry Juliette J Legrand Pierre P Krey Thomas T Rey Felix A FA
Structure (London, England : 1993) 20181108 1
The cellular fusion protein HAP2, which is structurally homologous to viral class II fusion proteins, drives gamete fusion across several eukaryotic kingdoms. Gamete fusion is a highly controlled process in eukaryotes, and is allowed only between same species gametes. In spite of a conserved architecture, HAP2 displays several species-specific functional regions that were not resolved in the available X-ray structure of the green alga Chlamydomonas reinhardtii HAP2 ectodomain. Here we present an ...[more]