Ontology highlight
ABSTRACT:
SUBMITTER: Santerre M
PROVIDER: S-EPMC6343720 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Cell cycle (Georgetown, Tex.) 20190106 2
Non-small cell lung cancer (NSCLC) represents about 85% of all lung cancer cases. Lung cancer is the most frequent non-AIDS-defining malignancies in HIV-infected patients. The mechanism of the increased risk for lung cancer in HIV-1 patients is poorly understood. HIV-1 Nef protein has been suggested to be one of the key players in HIV-related lung disease. In here, we showed the involvement of Nef protein in cell modifications such as fibroblasts (IMR-90) and normal (BEAS-2B) or cancerous (A549) ...[more]