Ontology highlight
ABSTRACT:
SUBMITTER: Alfatah M
PROVIDER: S-EPMC6345779 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Alfatah Mohammad M Wong Jin Huei JH Nge Choy Eng CE Kong Kiat Whye KW Low Kia Ngee KN Leong Chung Yan CY Crasta Sharon S Munusamy Madhaiyan M Chang Amanda Mun Leng AML Hoon Shawn S Ng Siew Bee SB Kanagasundaram Yoganathan Y Arumugam Prakash P
Scientific reports 20190124 1
We have isolated Hypoculoside, a new glycosidic amino alcohol lipid from the fungus Acremonium sp. F2434 belonging to the order Hypocreales and determined its structure by 2D-NMR (Nuclear Magnetic Resonance) spectroscopy. Hypoculoside has antifungal, antibacterial and cytotoxic activities. Homozygous profiling (HOP) of hypoculoside in Saccharomyces cerevisiae (budding yeast) revealed that several mutants defective in vesicular trafficking and vacuolar protein transport are sensitive to hypoculos ...[more]