Infant cortisol stress-response is associated with thymic function and vaccine response.
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ABSTRACT:
SUBMITTER: Huda MN
PROVIDER: S-EPMC6351220 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Infant cortisol stress-response is associated with thymic function and vaccine response.
Huda M Nazmul MN Ahmad Shaikh M SM Alam Md Jahangir MJ Khanam Afsana A Afsar Md Nure Alam MNA Wagatsuma Yukiko Y Raqib Rubhana R Stephensen Charles B CB Laugero Kevin D KD
Stress (Amsterdam, Netherlands) 20180622 1
Stress can impair T cell-mediated immunity. To determine if infants with high stress responses had deficits in T-cell mediated immunity, we examined the association of pain-induced cortisol responsiveness with thymic function and vaccine responses in infants. This study was performed among 306 (male = 153 and female = 153) participants of a randomized, controlled trial examining the effect of neonatal vitamin A supplementation on immune function in Bangladesh (NCT01583972). Salivary cortisol was ...[more]
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