Ontology highlight
ABSTRACT:
SUBMITTER: Li JSS
PROVIDER: S-EPMC6357765 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Li Joshua Shing Shun JSS Millard S Sean SS
Science advances 20190116 1
Alternative splicing increases the proteome diversity crucial for establishing the complex circuitry between trillions of neurons. To provide individual cells with different repertoires of protein isoforms, however, this process must be regulated. Previously, we found that the mutually exclusive alternative splicing of <i>Drosophila Dscam2</i> produces two isoforms (A and B) with unique binding properties. This splicing event is cell type specific, and the transmembrane proteins that it generate ...[more]